New functionalized maleopimarimides were prepared. Their cytotoxicity against tumor cell lines (HeLa, HEp-2) was studied. Diterpenoids 6, 9 , and 10 with allene fragments possessed the greatest cytotoxicity and could be considered lead compounds with potential antitumor activity.

中文翻译：

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一系列功能化马来酰亚胺的合成及细胞毒活性

制备了新的功能化马来酰亚胺。研究了它们对肿瘤细胞系（HeLa、HEp-2）的细胞毒性。带有丙二烯片段的二萜类化合物 6、9 和 10 具有最大的细胞毒性，可被视为具有潜在抗肿瘤活性的先导化合物。