A series of metal complexes of Zn(II) have been synthesized with newly synthesized biologically active 1,2,4-triazole Schiff bases derived from the condensation of 3-substituted-4-amino-5-mercapto-1,2,4-triazole with 8-formyl-7-hydroxy-4-methylcoumarin. The structure of the complexes has been proposed in the light of elemental analyses, spectroscopic data (IR, UV-Vis, ¹H NMR and FAB-mass), thermal studies. Electrochemical study of the complexes is also reported. All the complexes are soluble to limited extent in common organic solvents but soluble to larger extent in DMF and DMSO and are non-electrolytes in these two solvent. All these Schiff bases and their complexes have also been screened for their antibacterial (Escherichia. coli, S. aureus, S. pyogenes, P. aeruginosa and Salmonella typhi) and antifungal activities (Aspergillus niger, Aspergillus flavus and cladosporium) by MIC method. The brine shrimp bioassay was also carried out to study their in vitro cytotoxic properties.

中文翻译：

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1,2,4-三唑希夫碱锌（II）配合物的合成，理化研究和生物学研究

Zn（II）的一系列金属配合物已与新合成的具有生物活性的1,2,4-三唑Schiff碱合成，所述Schiff碱是由3-取代的4-氨基-5-巯基-1,2,4-缩合而成的。三唑与8-甲酰基-7-羟基-4-甲基香豆素。根据元素分析，光谱数据（IR，UV-Vis，¹ H NMR和FAB-mass）以及热学研究，提出了配合物的结构。还报道了配合物的电化学研究。所有的配合物在普通的有机溶剂中都可有限地溶解，但在DMF和DMSO中则可较大程度地溶解，并且在这两种溶剂中都是非电解质。还对所有这些席夫碱及其复合物的抗菌性进行了筛选（大肠杆菌，金黄色葡萄球菌，化脓性链球菌，铜绿假单胞菌和伤寒沙门氏菌）。）和抗微生物活性（黑曲霉，黄曲霉和枝孢菌）通过MIC方法检测。还进行了盐水虾生物测定以研究其体外细胞毒性特性。