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Hydrogels and Sponge Materials Based on Triblock Copolymers of Lactide and Ethylene Glycol
Doklady Chemistry ( IF 0.8 ) Pub Date : 2019-06-01 , DOI: 10.1134/s001250081906003x
Yu. D. Zagoskin , T. E. Grigoriev , S. V. Krasheninnikov , E. V. Cuevda , E. A. Gubareva , A. V. Bakirov , S. N. Chvalun

New techniques were developed for the preparation of spongy materials and hydrogels based on triblock copolymers of lactide and ethylene glycol with various molecular structures. The effect of composition of the initial copolymers and supramolecular structure on their mechanical characteristics and biocompatibility was studied. According to cytological studies, all materials had a high level of cell viability (CV). The possibility of obtaining hydrogels with elastic moduli of up to 4460 kPa, which is a record high value for such systems, was demonstrated.

中文翻译:

基于丙交酯和乙二醇三嵌段共聚物的水凝胶和海绵材料

开发了基于丙交酯和乙二醇的具有各种分子结构的三嵌段共聚物制备海绵状材料和水凝胶的新技术。研究了初始共聚物的组成和超分子结构对其机械特性和生物相容性的影响。根据细胞学研究,所有材料都具有高水平的细胞活力 (CV)。证明了获得弹性模量高达 4460 kPa 的水凝胶的可能性,这是此类系统的创纪录高值。
更新日期:2019-06-01
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