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Hydrogels and Sponge Materials Based on Triblock Copolymers of Lactide and Ethylene Glycol

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Abstract

New techniques were developed for the preparation of spongy materials and hydrogels based on triblock copolymers of lactide and ethylene glycol with various molecular structures. The effect of composition of the initial copolymers and supramolecular structure on their mechanical characteristics and biocompatibility was studied. According to cytological studies, all materials had a high level of cell viability (CV). The possibility of obtaining hydrogels with elastic moduli of up to 4460 kPa, which is a record high value for such systems, was demonstrated.

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Authors and Affiliations

  1. National Research Center “Kurchatov Institute”, 123182, Moscow, Russia

    Yu. D. Zagoskin, T. E. Grigoriev, S. V. Krasheninnikov, A. V. Bakirov & S. N. Chvalun

  2. Kuban State Medical University, Ministry of Health of Russia, 350063, Krasnodar, Russia

    E. V. Cuevda & E. A. Gubareva

  3. Enikolopov Institute of Synthetic Polymeric Materials, Russian Academy of Sciences, 117393, Moscow, Russia

    A. V. Bakirov & S. N. Chvalun

Authors
  1. Yu. D. Zagoskin
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  2. T. E. Grigoriev
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  3. S. V. Krasheninnikov
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  4. E. V. Cuevda
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  5. E. A. Gubareva
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  6. A. V. Bakirov
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  7. S. N. Chvalun
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Corresponding author

Correspondence to Yu. D. Zagoskin.

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Translated by Z. Svitanko

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Zagoskin, Y.D., Grigoriev, T.E., Krasheninnikov, S.V. et al. Hydrogels and Sponge Materials Based on Triblock Copolymers of Lactide and Ethylene Glycol. Dokl Chem 486, 149–151 (2019). https://doi.org/10.1134/S001250081906003X

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  • DOI: https://doi.org/10.1134/S001250081906003X

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