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Polyelectrolyte nanoparticles based on functionalized silica and pillar[5]arene derivatives for recognition of model proteins
Russian Chemical Bulletin ( IF 1.7 ) Pub Date : 2019-11-01 , DOI: 10.1007/s11172-019-2667-0
R. V. Ziatdinova , A. A. Nazarova , L. S. Yakimova , O. A. Mostovaya , V. I. Kalinin , Y. N. Osin , I. I. Stoikov

The paper reports the first synthesis of positively charged hybrid organic-inorganic silicon dioxide nanoparticles with an average particle diameter of 28 nm modified with 1-[3-(diethylamino)propyl]-3-[3-(triethoxysilyl)propyl]urea and pillar[5]arene derivatives containing negatively charged groups, which form nanoparticles with an average diameter of 40 nm in an aqueous solution. These nanoparticles were utilized in a new procedure developed for the preparation of mixed polyelectrolyte particles. Spectroscopic studies (UV spectroscopy, dynamic light scattering) showed that the resulting compounds are able to recognize biopolymers, proteins (bovine serum albumin and lysozyme).

中文翻译:

基于功能化二氧化硅和柱[5]芳烃衍生物的聚电解质纳米粒子用于识别模型蛋白

该论文首次合成了平均粒径为 28 nm 的带正电荷的杂化有机-无机二氧化硅纳米粒子,经 1-[3-(二乙氨基)丙基]-3-[3-(三乙氧基甲硅烷基)丙基]脲和柱[5]芳烃衍生物含有带负电荷的基团,在水溶液中形成平均直径为40 nm的纳米颗粒。这些纳米粒子被用于为制备混合聚电解质粒子而开发的新程序中。光谱研究(紫外光谱、动态光散射)表明,所得化合物能够识别生物聚合物、蛋白质(牛血清白蛋白和溶菌酶)。
更新日期:2019-11-01
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