To evaluate the safety and efficacy of Glycyrrhiza uralensis root extracts produced using artificial hydroponic and artificial hydroponic-field hybrid cultivation systems, we investigated anti-allergic action in mice using IgE-mediated immediate hypersensitivity. Hot water extracts obtained from the roots of Glycyrrhiza uralensis cultivated using two systems were orally administered at a dose of 100 mg/kg as glycyrrhizin (GL) and compared with the commercial crude drug, Glycyrrhizae Radix. Both the artificial hydroponic and artificial hydroponic-field hybrid cultivated root extracts showed anti-allergic effects on IgE-mediated immediate hypersensitivity in mice, as did the commercial crude drugs. These results highlight the potential for artificially cultivated roots of Glycyrrhiza uralensis to be used as an alternative medicinal source.

中文翻译：

---

使用人工水培和人工水培田间杂交培养系统生产的甘草根提取物的安全性和有效性评估III：热水提取物对小鼠IgE介导的超敏反应的抗过敏作用。

为了评估使用人工水培和人工水培田间杂交培养系统生产的甘草根提取物的安全性和有效性，我们使用IgE介导的速发型超敏反应研究了小鼠的抗过敏作用。将从口服甘草的根中提取的热水提取物（使用两种系统培养）以100 mg / kg的剂量作为甘草甜素（GL）口服，并与市售粗药甘草基进行比较。人工水培法和人工水培法混合栽培的根提取物对小鼠的IgE介导的速发型超敏反应均表现出抗过敏​​作用，市售粗药物也是如此。这些结果突显了人工栽培根的潜力。甘草被用作替代药物来源。