Abstract—The purpose of this investigation was to study the neurobiological effects of several interplanetary flight factors: hypogravity, which was modeled in a ground-based experiment using the conventional gravitational unloading technique, a 7-day anti-orthostatic hanging (AOH), and synchronous with it long-term gamma irradiation and high-energy protons. We analyzed the animal behavior in a number of tests: the open field, elevated plus maze, passive avoidance, Morris water test, and the exchange of monoamines in key brain structures. The most interesting and paradoxical result of our study is that in some cases effects were mitigated by the combined effect of radiation and microgravity, which manifests itself both in behavior and in neurochemical changes in all five studied brain structures, despite the fact that these structures play different roles in the performance of behavior. However, the isolated treatment with both radiation and AOH caused significant changes.

中文翻译：

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抗体位悬挂和不同电离辐射联合作用的神经生物学作用

摘要—这项研究的目的是研究几种行星际飞行因素的神经生物学作用：重力下降，该重力下降是使用常规重力卸载技术在地面实验中建模的，为期7天的抗直立悬挂（AOH）和同步它具有长期的伽马射线照射和高能质子。我们在许多测试中分析了动物的行为：旷野，高架迷宫，被动回避，莫里斯水测试以及关键脑部结构中单胺的交换。我们的研究最有趣，最矛盾的结果是，在某些情况下，辐射和微重力的共同作用减轻了效应，这在研究的所有五个大脑结构的行为和神经化学变化中均表现出来，尽管这些结构在行为表现中起着不同的作用。但是，用放射线和AOH进行的隔离处理引起了显着变化。