We report a case of a 15-month-old Japanese girl with Kawasaki disease (KD) associated with bacteremia caused by Streptococcus pneumoniae (S. pneumoniae) 12F (a nonvaccine serotype). The patient had completed the pneumococcal 13-valent conjugate vaccination according to the immunization schedule for children in Japan. She presented at the emergency department of our hospital with fever for 3 days and all other KD symptoms and was admitted. Despite the detection of S. pneumoniae 12F in the blood culture on admission, initial treatment for KD with 2 g/kg of intravenous immunoglobulin and 30 mg/kg/day of oral aspirin without antibiotic administration improved both KD symptoms and bacteremia. The patient did not develop coronary aneurysm. Even though there were no reports of KD with bacteremia caused by S. pneumoniae (except in our case), the presence of bacteremia may not affect the treatment response or coronary artery outcome if KD is appropriately treated.

中文翻译：

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川崎病与肺炎球菌感染有关

我们报告的一个15个月大的日本女孩与引起菌血症相关川崎病（KD）的情况下，肺炎链球菌（小号。肺炎）12F（一非疫苗血清型）。该患者已按照日本儿童的免疫计划完成了肺炎球菌13价结合物疫苗接种。她在我们医院急诊科出现了发烧3天和所有其他KD症状，并入院。尽管检测的小号。肺炎入院时在血液培养物中使用12F，用2 g / kg的静脉注射免疫球蛋白和30 mg / kg /天的口服阿司匹林（不使用抗生素）对KD进行初始治疗可改善KD症状和菌血症。该患者未发生冠状动脉瘤。即使尚无关于KD感染由S引起的菌血症的报道。如果我们对肺炎进行了适当的治疗，则菌血症的存在可能不会影响治疗反应或冠状动脉预后。