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Structure of an Arc-ane virus-like capsid.
Nature Neuroscience ( IF 21.2 ) Pub Date : 2020-01-17 , DOI: 10.1038/s41593-019-0580-3
Vivian Budnik 1 , Travis Thomson 1
Affiliation  

Recent findings unveil a viral-like mechanism for the transmission of synaptic plasticity signals involving the activity-regulated cytoskeleton-associated protein (Arc). Arc forms capsid-like particles that package RNA and are transported across synapses. Here Erlendsson et al. present a high-resolution structural representation of Arc capsids, enabling deeper analysis of their function.

中文翻译:

Arc-ane 病毒样衣壳的结构。

最近的研究结果揭示了一种类似于病毒的机制,用于传递涉及活性调节的细胞骨架相关蛋白 (Arc) 的突触可塑性信号。Arc 形成衣壳状颗粒,包装 RNA 并通过突触运输。这里 Erlendsson 等人。呈现了 Arc 衣壳的高分辨率结构表示,从而能够更深入地分析它们的功能。
更新日期:2020-01-17
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