Effects of Polygonum equisetiforme extracts against dichlorvos were investigated in the commercial clam Ruditapes decussatus. The toxicity of this pesticide was firstly tested in R. decussatus gill and digestive gland tissues using five doses varying from 0.05 to 1 mg/l during 2, 4, and 7 days. Results showed that 0.05 mg/l of DDVP induced oxidative stress and neurotoxicity in R. decussatus after 2 days of exposure. Investigations of the effects of P. equisetiforme extracts in R. decussatus exposed to 0.25 mg/l of DDVP were made in clams receiving three concentrations (0.009, 0.045, and 0.09 g/l) during 4 and 7 days. Antioxidant enzymes SOD and CAT as well as H2O2 content and AChE were quantified by colorimetric method. Four days of exposure to DDVP increased SOD and CAT activities and enhances H2O2 content. AChE levels decreased considerably following DDVP exposure, although a restoration in the enzyme activity was observed with P. equisetiforme extract (E3 = 0.09 g/l). Overall, P. equisetiforme extract at concentration (E1 = 0.009 g/l) prevents oxidative stress caused by DDVP, while 0.09 g/l of P. equisetiforme extract induced an effect similar to that obtained with DDVP alone. Nevertheless, this concentration was found effective for the restoration of the AChE activity.

中文翻译：

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何首乌提取物对敌敌畏（DDVP）诱导的商业蛤仔Ruditapes decussatus的氧化应激和神经毒性的解毒作用。

在商业蛤仔Ruditapes decussatus中研究了何首乌提取物对敌敌畏的影响。该农药的毒性首先在2天，4天和7天期间在0.05至1 mg / l的5种剂量下，在圆角。和消化腺组织中进行了测试。结果显示，暴露2天后，0.05 mg / l的DDVP诱导了拟南芥的氧化应激和神经毒性。在4天和7天期间，对接受三种浓度（0.009、0.045和0.09 g / l）的蛤进行了对马齿equi对虾提取物对0.25 mg / l DDVP暴露的影响的研究。用比色法定量测定了抗氧化酶SOD，CAT，H2O2和AChE的含量。DDVP暴露四天增加了SOD和CAT活性，并增加了H2O2含量。DDVP暴露后，AChE水平显着降低，尽管木贼疫霉提取物（E3 = 0.09 g / l）观察到酶活性有所恢复。总体而言，浓度为（E1 = 0.009 g / l）的马蹄疫提取物可防止由DDVP引起的氧化应激，而0.09 g / l的马蹄疫提取物诱导的作用与单独使用DDVP所获得的作用相似。然而，发现该浓度对于恢复AChE活性是有效的。