Polyvinyl alcohol/cellulose nanocrystals (CNC) and hydroxyapatite (HA) (PCH) were combined using an in situ method to fabricate porous scaffolds. CNC was extracted from sugarcane bagasse and the effect of HA on PVA/CNC composites was varied with 0, 0.5, 1 and 3 wt%. The scanning electron microscopy images of the PCH composites showed interior pores with pore channels, while the energy dispersive spectroscopy (EDS) results confirmed the increased HA content in the nanocomposite with a Ca/P ratio of 1.67. Porosity and the equilibrium swelling ratio were slightly affected by the HA content. The Fourier transform infrared spectra supported the EDS results by identifying significant peaks belonging to the HA curves of the PCH composites. The crystallinity revealed decreased crystal regions at higher HA content, whereas the mechanical behavior showed the improvement at 0.5 wt% of HA. Cytotoxicity with L929 demonstrated the compatibility of the PCH composites, with 85 ± 0.92% cell viability.

使用原位方法将聚乙烯醇/纤维素纳米晶体（CNC）和羟基磷灰石（HA）（PCH）合并在一起以制造多孔支架。从甘蔗渣中提取CNC，HA对PVA / CNC复合材料的影响随0、0.5、1和3 wt％的变化而变化。PCH复合材料的扫描电子显微镜图像显示带有孔通道的内部孔，而能量色散光谱（EDS）结果证实纳米复合材料中的HA含量增加，Ca / P比为1.67。HA含量对孔隙率和平衡溶胀率略有影响。傅立叶变换红外光谱通过鉴定属于PCH复合材料的HA曲线的重要峰来支持EDS结果。结晶度表明在高HA含量下晶体区域减少，而机械性能显示在HA的0.5 wt％时有改善。L929的细胞毒性表明PCH复合材料具有相容性，细胞活力为85±0.92％。