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The Effect of Hydroxyapatite Prepared by In Situ Synthesis on the Properties of Poly(Vinyl Alcohol)/Cellulose Nanocrystals Biomaterial

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Abstract

Polyvinyl alcohol/cellulose nanocrystals (CNC) and hydroxyapatite (HA) (PCH) were combined using an in situ method to fabricate porous scaffolds. CNC was extracted from sugarcane bagasse and the effect of HA on PVA/CNC composites was varied with 0, 0.5, 1 and 3 wt%. The scanning electron microscopy images of the PCH composites showed interior pores with pore channels, while the energy dispersive spectroscopy (EDS) results confirmed the increased HA content in the nanocomposite with a Ca/P ratio of 1.67. Porosity and the equilibrium swelling ratio were slightly affected by the HA content. The Fourier transform infrared spectra supported the EDS results by identifying significant peaks belonging to the HA curves of the PCH composites. The crystallinity revealed decreased crystal regions at higher HA content, whereas the mechanical behavior showed the improvement at 0.5 wt% of HA. Cytotoxicity with L929 demonstrated the compatibility of the PCH composites, with 85 ± 0.92% cell viability.

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Acknowledgements

This work was partially supported by the Center for Advanced Studies for Agriculture and Food, Institute for Advanced Studies, Kasetsart University Under the Higher Education Research Promotion and National Research University Project of Thailand, Office of the Higher Education Commission, Ministry of Education, Thailand. The authors are grateful to the Department of Biotechnology, Faculty of Agro-Industry, Kasetsart University, Bangkok Thailand for providing all laboratory equipment.

Funding

This study was funded by Center for Advanced Studies for Agriculture and Food, Institute for Advanced Studies, Kasetsart University Under the Higher Education Research Promotion and National Research University Project of Thailand, Office of the Higher Education Commission, Ministry of Education, Thailand.

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Authors and Affiliations

  1. Biotechnology of Biopolymers and Bioactive Compounds Special Research Unit, Department of Biotechnology, Faculty of Agro-Industry, Kasetsart University, Chatuchak, Bangkok, 10900, Thailand

    Panee Panyasiri, Nga Tien Lam & Prakit Sukyai

  2. Center for Advanced Studies for Agriculture and Food, Kasetsart University Institute for Advanced Studies, Kasetsart University (CASAF, NRU-KU), Bangkok, 10900, Thailand

    Panee Panyasiri & Prakit Sukyai

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  1. Panee Panyasiri
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  2. Nga Tien Lam
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Correspondence to Prakit Sukyai.

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Panyasiri, P., Lam, N.T. & Sukyai, P. The Effect of Hydroxyapatite Prepared by In Situ Synthesis on the Properties of Poly(Vinyl Alcohol)/Cellulose Nanocrystals Biomaterial. J Polym Environ 28, 141–151 (2020). https://doi.org/10.1007/s10924-019-01599-5

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