Abstract

This study aims the amperometric enzyme-free glucose sensing of interlayered Polyaniline nanosheets @reduced grapheme oxide (PANINS@rGO). Conductive PANINS were synthesized using in situ chemical oxidative polymerization method. The PANINS@rGO nanocomposite was prepared by the solution mixing method and as-synthesized material was fully examined using various spectroscopy and microscopy techniques. PANINS@rGO composite coated on screen-printed carbon electrode (SPCE) was studied for electrochemical behaviour for the detection of non-enzymatic glucose. The fabricated sensor matrix was tested towards detection of glucose efficacy using cyclic voltammetry (CV) and Chronoamperometry (CA) techniques in the presence of 0.1 M NaOH electrolyte in a range of 1–10 mM at an optimum working potential of 60 mV s⁻¹. PANINS@rGO/SPCE absorbed with high sensitivity (3448.27 μA mM⁻¹ cm⁻²) and excellent low detection limit (LOD) 30 nM, (S/N = 3). Furthermore, the obtained results of the proposed PANINS@rGO/SPCE fabricated a finite sensor for non-enzymatic glucose sensor. Thus this report proves the practical opportunities for the development of environmentally benign, cost effective and chemically stable electrode materials for sensors, which may be beneficial for the expansion of economically viable enzyme free electrochemical glucose sensor devices.

中文翻译：

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高灵敏度聚苯胺纳米片（PANINS）@rGO作为非酶葡萄糖传感器

摘要

这项研究的目的是对层间聚苯胺纳米片@还原石墨烯氧化物（PANINS @ rGO）进行无电流的无酶葡萄糖感测。用原位化学氧化聚合法合成了导电PANINS。通过溶液混合法制备PANINS @ rGO纳米复合材料，并使用各种光谱学和显微镜技术对合成后的材料进行全面检查。研究了涂在丝网印刷碳电极（SPCE）上的PANINS @ rGO复合材料的电化学行为，用于检测非酶促葡萄糖。使用循环伏安法（CV）和计时电流法（CA）技术，在1 Mm至10 mM范围内的0.1 M NaOH电解质的存在下，在60 mV s ^-1的最佳工作电位下，对制造的传感器矩阵进行了检测葡萄糖功效的测试。。PANINS @ rGO / SPCE以高灵敏度（3448.27μAmM ^-1  cm ^-2）和出色的30 nM低检测限（LOD）吸收（S / N = 3）。此外，所提出的PANINS @ rGO / SPCE的结果为非酶葡萄糖传感器制造了有限传感器。因此，本报告证明了开发用于传感器的环境友好，具有成本效益和化学稳定的电极材料的实际机会，这可能有利于经济上可行的无酶电化学葡萄糖传感器设备的扩展。