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The Fåhræus-Lindqvist effect in small blood vessels: how does it help the heart?
Journal of Biological Physics ( IF 1.8 ) Pub Date : 2019-12-01 , DOI: 10.1007/s10867-019-09534-4
Michela Ascolese 1 , Angiolo Farina 1 , Antonio Fasano 1, 2, 3
Affiliation  

The Fåhræus-Lindqvist effect is usually explained from a physical point of view with the so-called Haynes' marginal zone theory, i.e., migration of red blood cells (RBCs) to a core layer surrounded by an annular RBCs-free plasma layer. In this paper we show that the marginal layer, though causing a substantial reduction in flow resistance and increasing discharge, does not reduce the rate of energy dissipation. This fact is not surprising if one considers the electric analog of the flow in a vessel: a resistance reduction increases both the current intensity (i.e., the discharge) and the energy dissipation. This result is obtained by considering six rheological models that relate the blood viscosity to hematocrit (volume fraction occupied by erythrocytes). Some physiological implications are discussed.

中文翻译:

小血管中的 Fåhræus-Lindqvist 效应:它如何帮助心脏?

Fåhræus-Lindqvist 效应通常从物理角度用所谓的海恩斯边缘区理论来解释,即红细胞 (RBC) 迁移到由环形无红细胞血浆层包围的核心层。在本文中,我们表明边缘层虽然导致流动阻力的显着降低和排放量的增加,但并未降低能量耗散率。如果考虑容器中流动的电模拟,这一事实不足为奇:电阻降低会增加电流强度(即放电)和能量耗散。该结果是通过考虑将血液粘度与血细胞比容(红细胞所占的体积分数)相关联的六个流变模型而获得的。讨论了一些生理意义。
更新日期:2019-12-01
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