The study of innovative biodegradable implant materials is one of the most interesting research topics at the forefront in the area of biomaterials. Biodegradable implant materials in the human body can be gradually dissolved, absorbed, consumed or excreted, so there is no need for the secondary surgery to remove implants after the surgery regions have healed. However, most of the biodegradable materials, usually polymers, do not have good mechanical properties to be reliable for bearing the load of the body. Magnesium and its alloys due to the excellent biodegradability and biocompatibility as well as the suitable mechanical compatibility with human bone are very promising candidates for the development of temporary, degradable implants in load-bearing applications. However, Mg alloys are corrosion susceptible in a biological environment. Besides, the high corrosion rate and the low bioactivity of magnesium implants are the challenging problems, which need to be resolved before employing them in clinical applications. This paper provides a review of state-of-the-art of magnesium alloy implants for orthopedic and tissue engineering applications and describes recent progress in the design of novel structure design Mg alloys and potential approaches to improve their biodegradation performance.

中文翻译：

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可生物降解的镁合金作为临时的骨科植入物：综述。

创新的可生物降解植入材料的研究是生物材料领域最前沿的最有趣的研究主题之一。人体中可生物降解的植入物材料可以逐渐溶解，吸收，消耗或排泄，因此，在手术区域愈合后，无需进行二次手术即可去除植入物。但是，大多数可生物降解的材料（通常是聚合物）没有良好的机械性能，无法可靠地承受身体的负荷。镁及其合金由于具有出色的生物降解性和生物相容性以及与人体骨骼的适当机械相容性，因此非常适合在承重应用中开发可降解的临时植入物。但是，镁合金在生物环境中易受腐蚀。除了，镁植入物的高腐蚀速率和低生物活性是具有挑战性的问题，在临床应用中需要解决这些问题。本文概述了用于骨科和组织工程的镁合金植入物的最新技术，并描述了新型结构设计镁合金的设计最新进展以及提高其生物降解性能的潜在方法。