We report a case of classic HSE with early neurological relapse 7 days after onset of acyclovir treatment secondary to cerebral venous thrombosis (CVT). The development of CVT after meningoencephalitis has been described with neurotropic viruses such as HSV, HIV, or enteroviruses and also bacterial or fungal agents. CVT is probably the consequence of the inflammation secondary to these infections. A diagnosis of CVT, although rarely described, should be systematically suspected in patients with HSE who present no or only moderate improvement, or early relapse of symptoms despite adapted acyclovir treatment.

中文翻译：

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脑静脉血栓形成：单纯疱疹性脑炎的罕见并发症。

我们报告一例经典的HSE病例，其在阿昔洛韦治疗后继发于脑静脉血栓形成（CVT）后7天出现早期神经系统复发。脑膜脑炎后，CVT的发展已被描述为与嗜神经性病毒（例如HSV，HIV或肠病毒）以及细菌或真菌病原体有关。CVT可能是这些感染继发的炎症的结果。尽管很少进行描述，但尽管采用了阿昔洛韦治疗，但仍无或仅有中度改善或症状较早复发的HSE患者应系统地怀疑CVT的诊断。