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Cerebral venous thrombosis: a rare complication of herpes simplex encephalitis

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Abstract

We report a case of classic HSE with early neurological relapse 7 days after onset of acyclovir treatment secondary to cerebral venous thrombosis (CVT). The development of CVT after meningoencephalitis has been described with neurotropic viruses such as HSV, HIV, or enteroviruses and also bacterial or fungal agents. CVT is probably the consequence of the inflammation secondary to these infections. A diagnosis of CVT, although rarely described, should be systematically suspected in patients with HSE who present no or only moderate improvement, or early relapse of symptoms despite adapted acyclovir treatment.

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Authors

Contributions

MV collected the data. MV, OT, and FBS wrote the first manuscript draft. All authors were involved in the care of the patient. All authors participated in the interpretation of the data and writing of the final manuscript and all authors approved the final manuscript. FBS was responsible for the overall supervision of the present work.

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Correspondence to F. Bani-Sadr.

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The authors declare that they have no conflict of interest.

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Vedani, M., Toubas, O., Hentzien, M. et al. Cerebral venous thrombosis: a rare complication of herpes simplex encephalitis. J. Neurovirol. 26, 114–117 (2020). https://doi.org/10.1007/s13365-019-00778-3

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  • DOI: https://doi.org/10.1007/s13365-019-00778-3

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