It is well established that bacteria communicate between each other by using different mechanisms; among which, quorum sensing (QS) is the best known one. Indeed, intra- and intercellular communications of microorganisms, as well as the regulation of metabolism and reaction to the surrounding environmental conditions, are carried out by using different signaling molecules. N-Acyl homoserine lactones control the QS in Gram-negative bacteria, while Gram-positive bacteria use communicating peptides. These compounds, by diffusing through the bacterial membrane cell from the extracellular medium, directly or indirectly control the expression of specific genes that induce bacteria to react to their surrounding environment and stressing agents. In the case of lactic acid bacteria and bifidobacteria which are widely used in the dairy industry, QS is of extreme importance for their survival and the extent of their activity in the dairy matrix. Moreover, it is also via QS that these bacteria synthesize various antimicrobial agents such as bacteriocins. The aim of this review is to highlight the quorum sensing circuits involved in the communicating mechanisms of bacteria with emphasis on current applications of QS in lactic acid bacteria. More particularly, the implication of QS in the biosynthesis of bacteriocins by lactic acid bacteria will be detailed.

中文翻译：

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细菌传播机制中的群体感应电路及其在乳酸菌细菌合成细菌中的意义：综述。

众所周知，细菌可以通过不同的机制相互交流。其中，群体感应（QS）是最著名的一种。实际上，通过使用不同的信号分子来进行微生物的细胞内和细胞间通讯，以及调节代谢和对周围环境条件的反应。N-酰基高丝氨酸内酯控制革兰氏阴性细菌的QS，而革兰氏阳性细菌则使用通讯肽。这些化合物通过从细胞外介质扩散穿过细菌膜细胞，直接或间接控制诱导细菌对其周围环境和压力物质起反应的特定基因的表达。对于乳制品行业广泛使用的乳酸菌和双歧杆菌，QS对于它们的生存以及它们在乳制品基质中的活性范围至关重要。此外，这些细菌还通过QS合成各种抗菌剂，例如细菌素。这篇综述的目的是强调与细菌的传播机制有关的群体感应电路，重点是QS在乳酸菌中的当前应用。更具体地，将详细描述QS在乳酸菌生物合成细菌素中的意义。这篇综述的目的是强调与细菌的传播机制有关的群体感应电路，重点是QS在乳酸菌中的当前应用。更具体地，将详细描述QS在乳酸菌生物合成细菌素中的意义。这篇综述的目的是强调与细菌的传播机制有关的群体感应电路，重点是QS在乳酸菌中的当前应用。更具体地，将详细描述QS在乳酸菌生物合成细菌素中的意义。