The GATA family of transcription factors consists of six proteins (GATA1-6) which are involved in a variety of physiological and pathological processes. GATA1/2/3 are required for differentiation of mesoderm and ectoderm-derived tissues, including the haematopoietic and central nervous system. GATA4/5/6 are implicated in development and differentiation of endoderm- and mesoderm-derived tissues such as induction of differentiation of embryonic stem cells, cardiovascular embryogenesis and guidance of epithelial cell differentiation in the adult.

中文翻译：

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GATA转录因子在发育和疾病中的新兴作用

GATA 转录因子家族由参与多种生理和病理过程的六种蛋白质 (GATA1-6) 组成。GATA1/2/3 是分化中胚层和外胚层衍生组织所必需的，包括造血和中枢神经系统。GATA4/5/6 与内胚层和中胚层衍生组织的发育和分化有关，例如诱导胚胎干细胞分化、心血管胚胎发生和指导成人上皮细胞分化。