Abstract The research interests of the Hamblin Laboratory are broadly centered on the use of different kinds of light to treat many different diseases. Photodynamic therapy (PDT) uses the combination of dyes with visible light to produce reactive oxygen species and kill bacteria, cancer cells and destroy unwanted tissue. Likewise, UV light is also good at killing especially pathogens. By contrast, red or near-infrared light can have the opposite effect, to act to preserve tissue from dying and can stimulate healing and regeneration. In all these applications, nanotechnology is having an ever-growing impact. In PDT, self-assembled nano-drug carriers (micelles, liposomes, etc.) play a great role in solubilizing the photosensitizers, metal nanoparticles can carry out plasmon resonance enhancement, and fullerenes can act as photosensitizers, themselves. In the realm of healing, single-walled carbon nanotubes can be electrofocused to produce nano-electonic biomedical devices, and nanomaterials will play a great role in restorative dentistry.

中文翻译：

---

用于光动力疗法的纳米技术：来自麻省总医院和哈佛医学院威尔曼光医学中心 Michael R. Hamblin 博士实验室的观点

摘要 Hamblin 实验室的研究兴趣广泛地集中在使用不同种类的光来治疗许多不同的疾病上。光动力疗法 (PDT) 使用染料与可见光的组合来产生活性氧并杀死细菌、癌细胞并破坏不需要的组织。同样，紫外线也擅长杀死尤其是病原体。相比之下，红光或近红外光可能会产生相反的效果，起到保护组织免于死亡的作用，并可以刺激愈合和再生。在所有这些应用中，纳米技术的影响越来越大。在PDT中，自组装纳米药物载体（胶束、脂质体等）对光敏剂的增溶作用很大，金属纳米粒子可以进行等离子体共振增强，富勒烯可以作为光敏剂，他们自己。在愈合领域，单壁碳纳米管可以电聚焦生产纳米电子生物医学设备，纳米材料将在牙科修复中发挥重要作用。