Various techniques have been employed to entrap fragrant oils within microcapsules or microparticles in the food, pharmaceutical, and chemical industries for improved stability and delivery. In the present work, we describe the use of silk protein microparticles for encapsulating fragrant oils using ambient processing conditions to form an all-natural biocompatible matrix. These microparticles are stabilized via physical crosslinking, requiring no chemical agents, and are prepared with aqueous and ambient processing conditions using polyvinyl alcohol–silk emulsions. The particles were loaded with fragrant oils via direct immersion of the silk particles within an oil bath. The oil-containing microparticles were coated using alternating silk and polyethylene oxide layers to control the release of the oil from the microspheres. Particle morphology and size, oil loading capacity, release rates as well as silk–oil interactions and coating treatments were characterized. Thermal analysis demonstrated that the silk coatings can be tuned to alter both retention and release profiles of the encapsulated fragrance. These oil-containing particles demonstrate the ability to adsorb and controllably release oils, suggesting a range of potential applications including cosmetic and fragrance utility.

中文翻译：

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丝绸微粒中挥发性化合物的包封。

在食品，制药和化学工业中，已经采用了各种技术将香精油截留在微胶囊或微粒中，以提高稳定性和递送性。在当前的工作中，我们描述了使用丝蛋白微粒在环境条件下封装香精油以形成全天然生物相容性基质的用途。这些微粒通过物理交联而稳定，不需要化学试剂，并使用聚乙烯醇-丝绸乳液在水和环境条件下制备。通过将蚕丝颗粒直接浸入油浴中，使颗粒中充满香油。使用交替的丝和聚环氧乙烷层涂覆含油的微粒，以控制油从微球的释放。表征了颗粒的形貌和尺寸，载油量，释放速率以及丝油相互作用和涂层处理。热分析表明，可以调节丝涂层以改变包封的香料的保留和释放曲线。这些含油颗粒显示出吸附和可控释放油的能力，表明了一系列潜在的应用，包括化妆品和香料用途。