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Using water-soluble C60 fullerenes in anticancer therapy.
Cancer Nanotechnology ( IF 4.5 ) Pub Date : 2011-08-19 , DOI: 10.1007/s12645-011-0020-x
S V Prylutska 1 , A P Burlaka 2 , P P Klymenko 3 , I I Grynyuk 1 , Yu I Prylutskyy 1 , Ch Schütze 4 , U Ritter 4
Affiliation  

Growth experiments of transplanted malignant tumors in the presence of water-soluble C60 fullerenes were performed on groups of mice. It was found that C60 fullerenes efficiently inhibit the growth of transplanted malignant tumors. This behavior can be explained through their high antioxidant activity and the blocking of the specific cell receptors (for example, endothelial growth factor). The findings demonstrate the possibility of using C60 fullerenes in anticancer therapy.

中文翻译:

在抗癌治疗中使用水溶性C60富勒烯。

在水溶性C60富勒烯存在下对移植的恶性肿瘤进行了生长实验。发现C60富勒烯有效抑制移植的恶性肿瘤的生长。可以通过其高抗氧化剂活性和特定细胞受体(例如,内皮生长因子)的阻滞来解释这种行为。研究结果表明在抗癌治疗中使用C60富勒烯的可能性。
更新日期:2011-08-19
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