Bacillus Calmette–Guérin (BCG) is the only available vaccine against tuberculosis. As well as being an effective vaccine against tuberculosis, BCG also provides off-target protection against various pathogens. Here, we report a mechanism for BCG-mediated cross-protection against influenza A virus (IAV), which requires a dialogue between the innate and adaptive immune memory systems.

中文翻译：

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卡介苗疫苗针对肺部病毒感染的交叉保护机制

卡介苗 (BCG) 是唯一可用的结核病疫苗。卡介苗不仅是一种有效的结核疫苗，还可以针对各种病原体提供脱靶保护。在这里，我们报告了一种卡介苗介导的针对甲型流感病毒（IAV）的交叉保护机制，该机制需要先天性免疫记忆系统和适应性免疫记忆系统之间的对话。