Pharmacogenomics (PGx) is rapidly growing branch of molecular genetics with high potentials to influence therapeutics. This review evaluates knowledge and attitudes of medical and pharmacy students about PGx. A literature search was conducted in electronic databases and studies were selected by following precise eligibility criteria. After quality assessment, studies were reviewed systematically, and meta-analyses of proportions were performed to estimate response rates of students. Fifteen studies (5509 students; 69% [95% confidence interval (CI): 60%, 77%] females) were included. Among students, 28% [95%CI: 12, 46] had adequate PGx knowledge; 65% [95%CI: 55, 75] were willing to have PGx test for their own risk assessment; 78% [95%CI: 71, 84] had intention to incorporate PGx in future practice; and 32% [95%CI: 21, 43] were satisfied with current PGx component of curriculum. Age, advanced year of educational program, and more time spent in PGx education were positively associated with PGx knowledge and positive attitudes.

药物基因组学 (PGx) 是分子遗传学快速发展的一个分支，具有影响治疗的巨大潜力。本综述评估了医学和药学学生对 PGx 的知识和态度。在电子数据库中进行文献检索，并根据精确的资格标准选择研究。质量评估后，对研究进行系统审查，并对比例进行荟萃分析，以估计学生的反应率。纳入了 15 项研究（5509 名学生；69% [95% 置信区间 (CI)：60%、77%] 为女性）。在学生中，28% [95%CI: 12, 46] 拥有足够的 PGx 知识；65% [95%CI: 55, 75] 愿意接受 PGx 测试以评估自身风险；78% [95%CI: 71, 84] 有意将 PGx 纳入未来实践；32% [95%CI: 21, 43] 对当前 PGx 课程内容感到满意。年龄、教育计划的高年级以及花在 PGx 教育上的时间与 PGx 知识和积极态度呈正相关。