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Knowledge and attitudes of medical and pharmacy students about pharmacogenomics: a systematic review and meta-analysis

The Pharmacogenomics Journal volume 23, pages 127–133 (2023)Cite this article

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Abstract

Pharmacogenomics (PGx) is rapidly growing branch of molecular genetics with high potentials to influence therapeutics. This review evaluates knowledge and attitudes of medical and pharmacy students about PGx. A literature search was conducted in electronic databases and studies were selected by following precise eligibility criteria. After quality assessment, studies were reviewed systematically, and meta-analyses of proportions were performed to estimate response rates of students. Fifteen studies (5509 students; 69% [95% confidence interval (CI): 60%, 77%] females) were included. Among students, 28% [95%CI: 12, 46] had adequate PGx knowledge; 65% [95%CI: 55, 75] were willing to have PGx test for their own risk assessment; 78% [95%CI: 71, 84] had intention to incorporate PGx in future practice; and 32% [95%CI: 21, 43] were satisfied with current PGx component of curriculum. Age, advanced year of educational program, and more time spent in PGx education were positively associated with PGx knowledge and positive attitudes.

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The datasets used and analyzed during the current study are available from the corresponding author on reasonable request.

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Author information

Author notes

  1. These authors contributed equally: Chen Li, Xiaona Su.

Authors and Affiliations

  1. Department of Pharmacy, Daping Hospital, Army Medical University, Chongqing, 400042, China

    Chen Li

  2. Department of Oncology, Daping Hospital, Army Medical University, Chongqing, 400042, China

    Xiaona Su

  3. Department of Medical & Scientific Research, Daping Hospital, Army Medical University, Chongqing, 400042, China

    Qidi Sun

  4. Biomedical Analysis Center, Army Medical University, Chongqing, 400038, China

    Yi Huang

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Contributions

CL and QDS performed literature search, extracted data, and wrote the manuscript; XNS and YH synthesized and analyzed the data. XNS made a significant contribution in revising the manuscript. All authors read and approved the final manuscript.

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Correspondence to Yi Huang.

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Li, C., Su, X., Sun, Q. et al. Knowledge and attitudes of medical and pharmacy students about pharmacogenomics: a systematic review and meta-analysis. Pharmacogenomics J 23, 127–133 (2023). https://doi.org/10.1038/s41397-023-00306-x

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