Current compression-based optical coherence elastography (OCE) only measures the axial displacement of a tissue, although the tissue also undergoes lateral displacement and microstructural alteration by the compression. In this Letter, we demonstrate a new compression-based OCE method that visualizes not only axial displacement, but also lateral displacement and microstructural decorrelation (MSD). This method employs complex correlation-based displacement and MSD measurements. It is implemented in a swept-source optical coherence tomography system with an active submicrometer compression. The performance of the method was demonstrated by measuring the porcine carotid artery and esophagus. The results showed significant axial and lateral displacements in the tissues by compression. An MSD map demonstrates high-contrast mechanical-property imaging.

中文翻译：

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具有二维位移测量和局部变形可视化的压缩光学相干弹性成像

当前的基于压缩的光学相干弹性成像（OCE）仅测量组织的轴向位移，尽管组织也由于压缩而发生横向位移和微结构改变。在这封信中，我们演示了一种新的基于压缩的OCE方法，该方法不仅可视化轴向位移，还可视化了横向位移和微结构去相关（MSD）。该方法采用基于复杂相关性的位移和MSD测量。它在具有有源亚微米压缩功能的扫频光学相干断层扫描系统中实现。通过测量猪的颈动脉和食道证明了该方法的有效性。结果显示通过压缩，组织中明显的轴向和横向位移。MSD图展示了高对比度的机械性能成像。