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The etiology, diagnosis, and management of hyperhidrosis: A comprehensive review: Therapeutic options.
Journal of the American Academy of Dermatology ( IF 12.8 ) Pub Date : 2019-01-31 , DOI: 10.1016/j.jaad.2018.11.066
Shiri Nawrocki 1 , Jisun Cha 1
Affiliation  

Hyperhidrosis (HH) is a chronic disorder of excess sweat production that may have a significant adverse effect on quality of life. A variety of treatment modalities currently exist to manage HH. Initial treatment includes lifestyle and behavioral recommendations. Antiperspirants are regarded as the first-line therapy for primary focal HH and can provide significant benefit. Iontophoresis is the primary remedy for palmar and plantar HH. Botulinum toxin injections are administered at the dermal-subcutaneous junction and serve as a safe and effective treatment option for focal HH. Oral systemic agents are reserved for treatment-resistant cases or for generalized HH. Energy-delivering devices such as lasers, ultrasound technology, microwave thermolysis, and fractional microneedle radiofrequency may also be utilized to reduce focal sweating. Surgery may be considered when more conservative treatments have failed. Local surgical techniques, particularly for axillary HH, include excision, curettage, liposuction, or a combination of these techniques. Sympathectomy is the treatment of last resort when conservative treatments are unsuccessful or intolerable, and after accepting secondary compensatory HH as a potential complication. A review of treatment modalities for HH and a sequenced approach are presented.

中文翻译:

多汗症的病因,诊断和处理:综合综述:治疗选择。

多汗症(HH)是出汗过多的慢性疾病,可能对生活质量产生重大不利影响。当前存在多种治疗HH的治疗方式。初始治疗包括生活方式和行为建议。止汗剂被认为是原发灶性HH的一线治疗,可带来显着益处。离子电渗疗法是手掌和足底HH的主要治疗方法。肉毒杆菌毒素注射在皮下-皮下连接处进行,可作为局灶性HH的安全有效治疗选择。口服全身性药物保留用于难治性病例或全身性HH。诸如激光,超声技术,微波热分解和微针射频分数之类的能量传递装置也可以用来减少局部出汗。当更保守的治疗失败时,可以考虑手术。局部手术技术,特别是腋窝HH手术,包括切除,刮除,吸脂或这些技术的结合。当保守治疗不成功或无法忍受,并且接受继发性代偿性HH作为潜在并发症后,交感神经切除术是最后的治疗方法。介绍了HH的治疗方式和顺序方法的综述。
更新日期:2019-08-14
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