Ten undescribed 9,19-cycloartane type triterpenoid glycosides (cimdahxynoside A-J) and five known analogues were obtained from the phytochemical research on the roots of Actaea dahurica (syn. Cimicifuga dahurica). All compounds were characterised by spectroscopic experiments, chemical method and X-ray Single-crystal diffraction analysis. Cimdahxynoside A represented the first X-ray crystallography of 9,19-cycloartane type triterpenoid diglycoside. The cytotoxicity of all compounds were tested against five human cancer cell lines. Cimdahxynoside F showed significant cytotoxicity, with IC50 values between 6.6 and 9.9 μM.

中文翻译：

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来自 Actaea dahurica 根的细胞毒性 9,19-环磷灰石型三萜糖苷

从对Actaea dahurica (syn. Cimicifuga dahurica) 根部的植物化学研究中获得了10 种未描述的9,19-环阿坦型三萜糖苷(cimdahxynoside AJ) 和5 种已知的类似物。所有化合物均通过光谱实验、化学方法和X射线单晶衍射分析进行表征。Cimdahxynoside A 代表了 9,19-环甲烷型三萜二糖苷的第一个 X 射线晶体学。针对五种人类癌细胞系测试了所有化合物的细胞毒性。Cimdahxynoside F 显示出显着的细胞毒性，IC50 值介于 6.6 和 9.9 μM 之间。