Regional variation in treatment paradigms for gastric adenocarcinoma has attracted a great deal of interest. Between Asia and the West, major differences have been identified in tumor biology, implementation of screening programs, extent of surgical lymphadenectomy, and routine use of neoadjuvant versus adjuvant treatment strategies. Minimally invasive techniques, including both laparoscopic and robotic platforms, have been studied in both regions, with attention to safety, feasibility, and long-term oncologic outcomes. The purpose of this review is to discuss advances in the understanding of the etiology and underlying biology of gastric cancer, as well as the current state of management, focusing on the differences between Asia and the West.

中文翻译：

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亚洲和西方的胃癌病因学和管理。

胃腺癌的治疗范例的区域差异引起了人们的极大兴趣。在亚洲和西方国家之间，在肿瘤生物学，筛查计划的实施，外科淋巴结清扫术的范围以及新辅助疗法与辅助治疗策略的常规使用之间已发现了主要差异。在这两个地区都研究了包括腹腔镜和机器人平台在内的微创技术，并关注安全性，可行性和长期肿瘤学成果。这篇综述的目的是讨论对胃癌的病因和基础生物学以及目前的治疗状态的理解，重点是亚洲和西方之间的差异。