The detection of Clostridioides difficile in inflammatory bowel disease (IBD) patients is a common occurrence, in part due to the standard clinical practice of testing for the presence of C. difficile during acute IBD exacerbations. Given the clinical overlap between C. difficile infections and acute IBD exacerbations (ie, increased frequency of loose stools, abdominal pain), it is hard to differentiate C. difficile infections versus colonizations in patients with underlying IBD who test positive for C. difficile. Here, we review the epidemiology, clinical presentation, risk factors, diagnosis, treatment, and outcomes of IBD patients with positive C. difficile tests.

中文翻译：

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艰难梭菌感染与炎症性肠病之间的交界处。

在炎症性肠病（IBD）患者中难辨梭状芽胞杆菌的检测是一种普遍现象，部分原因是在急性IBD急性发作期间检测难辨梭状芽胞杆菌存在的标准临床实践。鉴于艰难梭菌感染与急性IBD加重之间存在临床重叠（即，大便稀少，腹痛增加），很难区分艰难梭菌感染与难辨梭状芽胞杆菌呈阳性的潜在IBD患者中的定植。在这里，我们回顾了艰难梭菌检测呈阳性的IBD患者的流行病学，临床表现，危险因素，诊断，治疗和结局。