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Isolation of Nontuberculous Mycobacteria in Southeast Asian and African Human Immunodeficiency Virus-infected Children With Suspected Tuberculosis.
Clinical Infectious Diseases ( IF 8.2 ) Pub Date : 2019-05-02 , DOI: 10.1093/cid/ciy897
Laurence Borand 1 , Agathe de Lauzanne 1 , Ngoc Lan Nguyen 2 , Sokleaph Cheng 3 , Thu Hang Pham 4 , Sara Eyangoh 5 , Abdoul-Salam Ouedraogo 6 , Vibol Ung 7, 8 , Philippe Msellati 9 , Mathurin Tejiokem 10 , Boubacar Nacro 11 , Malin Inghammar 1, 12 , Bunnet Dim 1 , Christophe Delacourt 13 , Sylvain Godreuil 14, 15 , Stéphane Blanche 16 , Olivier Marcy 1, 17 ,
Affiliation  

We enrolled 427 human immunodeficiency virus-infected children (median age, 7.3 years), 59.2% severely immunodeficient, with suspected tuberculosis in Southeast Asian and African settings. Nontuberculous mycobacteria were isolated in 46 children (10.8%); 45.7% of isolates were Mycobacterium avium complex. Southeast Asian origin, age 5-9 years, and severe immunodeficiency were independently associated with nontuberculous mycobacteria isolation. CLINICAL TRIALS REGISTRATION NCT01331811.

中文翻译:

东南亚和非洲人免疫缺陷病毒感染的疑似结核病儿童的非结核分枝杆菌的分离。

我们招募了427名人类免疫缺陷病毒感染的儿童(中位年龄为7.3岁),其中59.2%的严重免疫缺陷儿童在东南亚和非洲地区患有结核病。在46名儿童(10.8%)中分离出了非结核分枝杆菌;分离株中有45.7%为鸟分枝杆菌复合物。东南亚血统,5-9岁的年龄和严重的免疫缺陷与非结核分枝杆菌的分离独立相关。临床试验注册NCT01331811。
更新日期:2019-05-16
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