Accelerometry has become a mainstay approach for objectively monitoring children’s physical activity and sedentary time in epidemiological studies. The magnitude of effort underlying successful data collection, management and treatment is prodigious and its complexity has been associated with increasingly diverse methodological choices that, while defensible relative to specific research questions, conspire to undermine the ability to compare results between studies. Although respecting widespread calls for best practices, it is also important to openly share tools and resources supporting potential improvements to research practice and study design, thus allowing others to replicate, further improve, and/or otherwise build on this foundation. The International Study of Childhood Obesity, Lifestyle and the Environment (ISCOLE) is a large multinational study that included accelerometer-based measures of physical activity, sedentary time and sleep. This review summarizes the unique contributions of ISCOLE to the advancement of accelerometry in large studies of children’s behavior, and in particular: (1) open-access publication of the ISCOLE accelerometry Manual of Operations; (2) 24-h waist-worn accelerometry protocol; (3) identification and extraction of nocturnal total sleep episode time (with open access to editable SAS syntax); (4) development of the first interpretive infrastructure for identifying and defining an evolved list of sleep-related variables from 24-h waist-worn accelerometry; (5) provision of a detailed model for reporting accelerometer paradata (administrative data related to accelerometry); and (6) cataloging the most detailed and defensible list of accelerometry-derived physical activity and sedentary time variables to date. The novel tools and resources associated with these innovations are shared openly in an effort to support methodological harmonization and overall advancement of accelerometry in large epidemiological studies.

在流行病学研究中，加速度计已成为客观监测儿童身体活动和久坐时间的主要手段。成功收集，管理和处理数据的巨大努力是巨大的，其复杂性已与越来越多的方法选择相关联，尽管相对于特定的研究问题可以辩护，但它们合谋破坏了研究之间比较结果的能力。尽管尊重对最佳实践的广泛呼吁，但公开共享工具和资源以支持对研究实践和研究设计的潜在改进也很重要，从而允许其他人在此基础上进行复制，进一步改进和/或以其他方式建立基础。国际儿童肥胖研究，生活方式与环境（ISCOLE）是一项大型的跨国研究，其中包括基于加速度计的身体活动，久坐时间和睡眠量度。这篇综述总结了ISCOLE在儿童行为的大规模研究中对加速测量的独特贡献，特别是：（1）ISCOLE加速测量操作手册的开放获取；（2）24小时腰部加速计协议；（3）识别和提取夜间总睡眠发作时间（可访问可编辑的SAS语法）；（4）开发第一个解释性基础结构，以识别和定义从24小时腰穿式加速度计得出的与睡眠有关的变量的清单；（5）提供详细模型来报告加速度计参数（与加速度计有关的管理数据）；（6）归类迄今为止最详细，最有根据的加速度计衍生的体育活动和久坐时间变量的清单。与这些创新相关的新颖工具和资源被公开共享，以支持大型流行病学研究中方法的协调和加速度计的整体进步。