The Hansen solubility parameters (HSPs) are a way of evaluating the compatibility of functional particles with a liquid phase. Precipitation and dynamic light scattering methods are commonly used to evaluate the HSPs of particle surfaces. However, measuring the HSPs of highly dense, large, or non-spherical particles by the above-mentioned techniques is difficult. Here, we applied a capillary permeation method for HSP measurements. We confirmed the effectiveness of the capillary penetration method by measuring 1-µm-spherical silica particles, which we also measured by dynamic light scattering. The HSPs determined by the capillary penetration and dynamic light scattering methods were similar. Our new method will enable simple measurements of the HSPs of dense and large particles to facilitate future applications of such particles.

汉森溶解度参数（HSP）是评估功能性颗粒与液相相容性的一种方法。沉淀法和动态光散射法通常用于评估颗粒表面的热休克蛋白。然而，通过上述技术来测量高密度，大或非球形颗粒的HSP是困难的。在这里，我们将毛细管渗透方法用于HSP测量。我们通过测量1 µm球形二氧化硅颗粒（也通过动态光散射测量）证实了毛细管渗透方法的有效性。通过毛细管渗透法和动态光散射法测定的热休克蛋白相似。我们的新方法将能够对稠密和大颗粒的HSP进行简单测量，以促进此类颗粒的未来应用。