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Impact of the supine position versus left horizontal position on colonoscopy insertion: a 2-center, randomized controlled trial.
Gastrointestinal Endoscopy ( IF 6.7 ) Pub Date : 2019-01-18 , DOI: 10.1016/j.gie.2019.01.009
Shengbing Zhao 1 , Xia Yang 2 , Qianqian Meng 1 , Shuling Wang 1 , Jun Fang 3 , Wei Qian 1 , Tian Xia 1 , Peng Pan 1 , Zhijie Wang 1 , Lun Gu 1 , Xin Chang 1 , Duowu Zou 4 , Zhaoshen Li 1 , Yu Bai 1
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BACKGROUND AND AIMS Colonoscopy insertion is painful for some patients and is one of the main barriers to screening colonoscopy. Few studies have assessed the impact of the supine position (SP) on colonoscopy insertion, especially for unsedated patients. The aim of this randomized controlled trial was to clarify this issue. METHODS Unsedated patients were randomized to SP or left horizontal position (LHP) as the starting position of colonoscopy insertion. The primary outcome measure was cecal intubation time (CIT), and the secondary outcome measures were descending colon intubation time (DIT), pain score of patients, difficulty score according to the endoscopist, and patients' acceptance of unsedated colonoscopy. RESULTS A total of 347 patients were randomized to the SP group (175) or the LHP group (172). The CIT in the SP group was significantly shorter than that in the LHP group (275.0 seconds [interquartile range (IQR), 234.0-328.5 seconds] versus 316.0 seconds [IQR, 261.0-370.0 seconds], P < .001). The DIT was also shorter in the SP group (64.5 seconds [IQR, 52.0-86.3 seconds] versus 74.0 seconds [IQR, 62.0-92.0 seconds], P = .001). Compared with the LHP, the SP had a lower pain score (3.3 versus 3.9, P = .002), a lower difficulty score (3.1 versus 3.7, P < .001), a lower frequency of position change (7.1% versus 38.0%, P < .001), and less need for abdominal compression (39.1% versus 45.5%, P = .02). SP was the only modifiable and independent factor identified to reduce CIT and pain score and improve patients' acceptance of unsedated colonoscopy. CONCLUSIONS As an economical and convenient method, SP can reduce CIT, ease pain, and improve patients' acceptance of unsedated colonoscopy. (Clinical trial registration number: NCT03289442.).

中文翻译:

仰卧位与左侧水平位对结肠镜检查插入的影响:一项2中心,随机对照试验。

背景和目的结肠镜检查的插入对于某些患者来说是痛苦的,并且是结肠镜检查筛查的主要障碍之一。很少有研究评估仰卧位(SP)对结肠镜检查的影响,特别是对于未镇静的患者。这项随机对照试验的目的是澄清这个问题。方法将未镇静的患者随机分配至SP或左水平位置(LHP)作为结肠镜检查插入的起始位置。主要结局指标为盲肠插管时间(CIT),次要结局指标为降结肠插管时间(DIT),患者疼痛评分,根据内镜医师的难度评分以及患者接受未镇静结肠镜检查的结果。结果共有347例患者被随机分为SP组(175例)或LHP组(172例)。SP组的CIT明显短于LHP组(275.0秒[四分位间距(IQR),234.0-328.5秒]与316.0秒[IQR,261.0-370.0秒],P <.001)。SP组的DIT也较短(64.5秒[IQR,52.0-86.3秒]与74.0秒[IQR,62.0-92.0秒],P = .001)。与LHP相比,SP的疼痛评分较低(3.3对3.9,P = .002),难度评分较低(3.1对3.7,P <.001),位置改变的频率较低(7.1%对38.0%) ,P <.001),并且对腹部压缩的需求更少(39.1%对45.5%,P = .02)。SP是唯一可以改变的独立因素,可降低CIT和疼痛评分并提高患者对未镇静结肠镜检查的接受度。结论作为一种经济方便的方法,SP可以降低CIT,减轻疼痛,并提高患者对未镇静结肠镜检查的接受度。(临床试验注册号:NCT03289442。)。
更新日期:2019-01-18
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