当前位置：
X-MOL 学术
›
Food Funct.
›
论文详情
Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
Agaricus blazei Murrill from Brazil: an ingredient for nutraceutical and cosmeceutical applications
Food & Function ( IF 5.1 ) Pub Date : 2019-01-15 00:00:00 , DOI: 10.1039/c8fo02461h Oludemi Taofiq 1, 2, 3, 4, 5 , Francisca Rodrigues 6, 7, 8, 9, 10 , Lillian Barros 1, 2, 3, 4 , Rosane M. Peralta 11, 12, 13, 14, 15 , Maria F. Barreiro 1, 2, 3, 4, 5 , Isabel C. F. R. Ferreira 1, 2, 3, 4 , M. Beatriz P. P. Oliveira 6, 7, 8, 9, 10
Food & Function ( IF 5.1 ) Pub Date : 2019-01-15 00:00:00 , DOI: 10.1039/c8fo02461h Oludemi Taofiq 1, 2, 3, 4, 5 , Francisca Rodrigues 6, 7, 8, 9, 10 , Lillian Barros 1, 2, 3, 4 , Rosane M. Peralta 11, 12, 13, 14, 15 , Maria F. Barreiro 1, 2, 3, 4, 5 , Isabel C. F. R. Ferreira 1, 2, 3, 4 , M. Beatriz P. P. Oliveira 6, 7, 8, 9, 10
Affiliation
|
Operations for sorting mushrooms at the industrial level usually generate large amounts of bio-residues not conforming to strict morphological criteria for commercial purposes, even though their biological content is not compromised. In this context, the present work aimed at evaluating the potential for reutilizing industrially discarded Agaricus blazei Murill (ABM). Thus, the content of essential nutrients and the chemical composition were determined, and MTT and LDH assays were used to evaluate the viability and cell death of Caco-2 and HT29 cell lines of an ethanolic extract prepared from ABM (preliminary safety tests for nutraceutical applications). The extract was incorporated into a semi-solid base cosmetic cream and cell viability effects of the extract, and of the final cream formulation, on a keratinocyte cell line (HaCaT) were studied (preliminary safety tests for cosmeceutical applications). Essential nutrients, such as proteins and carbohydrates, and a low fat content were determined for ABM. Twenty-two fatty acids were detected, with polyunsaturated fatty acids (PUFA) (∼53%) being the most abundant fraction. The cell viabilities of Caco-2 and HT29 cells were maintained up to 100 μg mL−1. After incorporation into the base cream, a formulation with a pale yellow colour and favourable pH was obtained. The cell viability of HaCaT cells in the presence of the extract and the final cream formulation was maintained in a concentration dependent manner, which indicates the safety of this extract for cosmeceutical applications. The results suggest that ABM residues can be used as an inexpensive and sustainable source of nutraceutical and cosmeceutical ingredients.
中文翻译：
来自巴西的姬松茸：用于营养保健和药妆的原料
在工业水平上对蘑菇进行分选的操作通常会产生大量不符合商业用途严格形态学标准的生物残留物，即使其生物学含量没有受到损害。在这种情况下，本工作旨在评估重新利用工业弃置姬松茸的潜力。穆里尔（ABM）。因此，确定了必需营养素的含量和化学组成，并使用MTT和LDH分析评估了ABM制备的乙醇提取物的Caco-2和HT29细胞系的生存力和细胞死亡（营养保健品的初步安全性测试） ）。将提取物掺入半固体基础美容霜中，研究提取物和最终霜剂对角质形成细胞系（HaCaT）的细胞生存力影响（用于药妆应用的初步安全性测试）。确定了ABM的必需营养素，例如蛋白质和碳水化合物，以及低脂肪含量。检测到22种脂肪酸，其中多不饱和脂肪酸（PUFA）（〜53％）是含量最高的部分。-1。掺入基础乳霜后，获得具有浅黄色和良好pH的制剂。在存在提取物和最终的乳膏制剂的情况下，HaCaT细胞的细胞活力以浓度依赖性的方式维持，这表明该提取物在药妆应用中的安全性。结果表明，ABM残留物可用作营养保健品和药妆配料的廉价且可持续的来源。
更新日期：2019-01-15
中文翻译：
来自巴西的姬松茸：用于营养保健和药妆的原料
在工业水平上对蘑菇进行分选的操作通常会产生大量不符合商业用途严格形态学标准的生物残留物，即使其生物学含量没有受到损害。在这种情况下，本工作旨在评估重新利用工业弃置姬松茸的潜力。穆里尔（ABM）。因此，确定了必需营养素的含量和化学组成，并使用MTT和LDH分析评估了ABM制备的乙醇提取物的Caco-2和HT29细胞系的生存力和细胞死亡（营养保健品的初步安全性测试） ）。将提取物掺入半固体基础美容霜中，研究提取物和最终霜剂对角质形成细胞系（HaCaT）的细胞生存力影响（用于药妆应用的初步安全性测试）。确定了ABM的必需营养素，例如蛋白质和碳水化合物，以及低脂肪含量。检测到22种脂肪酸，其中多不饱和脂肪酸（PUFA）（〜53％）是含量最高的部分。-1。掺入基础乳霜后，获得具有浅黄色和良好pH的制剂。在存在提取物和最终的乳膏制剂的情况下，HaCaT细胞的细胞活力以浓度依赖性的方式维持，这表明该提取物在药妆应用中的安全性。结果表明，ABM残留物可用作营养保健品和药妆配料的廉价且可持续的来源。
京公网安备 11010802027423号