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Vancomycin use in surrounding patients during critical illness and risk for persistent colonization with vancomycin-resistant Enterococcus.
Journal of Hospital Infection ( IF 6.9 ) Pub Date : 2019-01-11 , DOI: 10.1016/j.jhin.2019.01.008
P Zachariah 1 , D E Freedberg 2
Affiliation  

The optimal duration of contact precautions for vancomycin-resistant enterococcus (VRE)-colonized patients is uncertain and individual patient characteristics alone may not predict risk of prolonged colonization. Using a cohort of adult patients who underwent testing for VRE at intensive care unit (ICU) admission, we tested the association between local (unit-level) vancomycin use and persistent colonization with VRE. Higher unit-level vancomycin use significantly prolonged VRE colonization (P=0.03) independent of patient-level vancomycin use and unit VRE density.



中文翻译:

在危重疾病期间,周围患者使用万古霉素,并有耐万古霉素的肠球菌持续定植的风险。

万古霉素耐药肠球菌(VRE)定植患者的最佳预防接触时间不确定,并且仅根据患者的个人特征可能无法预测长期定植的风险。使用一组在重症监护病房(ICU)入院接受VRE测试的成年患者,我们测试了局部(单位水平)万古霉素的使用与VRE持续定植之间的关联。与患者水平使用万古霉素和单位VRE密度无关,更高水平使用万古霉素可显着延长VRE定植时间(P = 0.03)。

更新日期:2019-06-20
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