As an essential biodegradable polyester species, poly(butylene succinate) (PBS) is restricted for wider applications due to its low thermal/mechanical properties and unsatisfactory (bio)degradability. Current practice of introducing either stiff or flexible building blocks into PBS main chains remains challenging to achieve a synergistic enhancement of the thermal and (bio)degradability of this material. We herewith report a series of PBS copolyesters based on the carbohydrate-derived isosorbide (1,4:3,6-dianhydro-_D-glucidol, IS) (PBIS) by utilizing its unique intrinsic characters of being rigid and hydrophilic. The target copolyesters were constructed with a broad scope of IS content (0–100 mol%) and with random microstructures. The M_n values and the intrinsic viscosities of these polyesters are in the scopes of 7300–38,700 g mol⁻¹ and 0.33–0.82 dL g⁻¹, respectively. The results shown in this work clearly demonstrated that the presence of IS enhances the T_g values almost linearly and simultaneously promotes (neutral, acidic) hydrolytic and enzymatic degradations (with porcine pancreas) of the copolyesters. PBIS copolyester containing 20 mol% IS displays comparable hydrolytic and enzymatic degradation rates with those of PBSA (20 mol% adipic acid), but a substantially 23 °C higher T_g value. Detailed characterization of the molecular structures, micro-sequential structures, molecular weights and polydipersities, thermal properties, hydrophilicities and (bio)degradability are provided. The (bio)degradation and degradation mechanism study of these copolyesters are reported for the first time.

作为必不可少的可生物降解的聚酯种类，聚丁二酸丁二酯（PBS）由于其低的热/机械性能和不令人满意的（生物）可降解性而被限制用于更广泛的应用。目前，将刚性或柔性结构单元引入PBS主链的实践仍然具有挑战性，以实现这种材料的热降解和（生物）降解性的协同增效。我们据此报道了一系列基于碳水化合物衍生的异山梨醇酯（1,4：3,6-二脱水_-D-葡糖醇，IS）（PBIS）的PBS共聚酯，它利用了其独特的固有特性，即刚性和亲水性。所构建的目标共聚酯具有广泛的IS含量范围（0–100 mol％），并且具有无规的微观结构。在中号_ñ这些聚酯的数值和特性粘度分别在7300–38,700 g mol ^-1和0.33–0.82 dL g ^-1的范围内。这项工作中显示的结果清楚地表明，IS的存在几乎线性地提高了T _g值，同时促进了共聚酯的（中性，酸性）水解和酶促降解（猪胰脏）。含有20 mol％IS的PBIS共聚酯显示出与PBSA（20 mol％己二酸）相当的水解和酶促降解速率，但T _g却高出23°C价值。提供了分子结构，微序列结构，分子量和多分散性，热性能，亲水性和（生物）降解性的详细表征。首次报道了这些共聚酯的（生物）降解和降解机理研究。