Effective use of genetic and genomic data in cancer prevention and treatment depends on adequate communication with patients and the public. Although relevant empirical work has emerged, the scope and outcomes of this communication research have not been characterized. We conducted a comprehensive scoping review of recent published research (2010-2017) on communication of cancer-related genetic and genomic testing (CGT) information. Searches in six databases revealed 9243 unique records; 513 papers were included. Most papers utilized an observational quantitative design; fewer utilized an experimental design. More attention has been paid to outcomes of CGT results disclosure than to decision making regarding CGT uptake or the process of results disclosure. Psychosocial outcomes were most common across studies. This literature has a strong focus on BRCA1/2, with few papers focused on Lynch syndrome or next-generation technologies. Women, Caucasians, older adults, and those of higher socioeconomic status were overrepresented. Research gaps identified include the need for studies on the process of CGT communication; examining behavioral, decision making, and communication outcomes; and inclusion of diverse populations. Addressing these gaps can help improve the use of genomics in cancer control and reduce disparities in access to and use of CGT.

中文翻译：

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基因组学和精准医学时代的癌症传播研究：范围审查。

在癌症预防和治疗中有效使用遗传和基因组数据取决于与患者和公众的充分沟通。尽管已经出现了相关的实证工作，但该传播研究的范围和结果尚未确定。我们对最近发表的关于癌症相关基因和基因组检测 (CGT) 信息交流的研究 (2010-2017) 进行了全面的范围审查。在六个数据库中的搜索显示了 9243 条唯一记录；513篇论文被收录。大多数论文采用观察定量设计。较少使用实验设计。更多关注 CGT 结果披露的结果，而不是有关 CGT 吸收或结果披露过程的决策。心理社会结果在研究中最为常见。该文献重点关注 BRCA1/2，很少有论文关注林奇综合征或下一代技术。女性、高加索人、老年人和社会经济地位较高的人比例过高。确定的研究差距包括需要对 CGT 沟通过程进行研究；检查行为、决策和沟通结果；和包容不同的人群。解决这些差距有助于改善基因组学在癌症控制中的应用，并减少 CGT 的获取和使用方面的差异。和沟通结果；和包容不同的人群。解决这些差距有助于改善基因组学在癌症控制中的应用，并减少 CGT 的获取和使用方面的差异。和沟通结果；和包容不同的人群。解决这些差距有助于改善基因组学在癌症控制中的应用，并减少 CGT 的获取和使用方面的差异。