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The brain in flux: Genetic, physiologic, and therapeutic perspectives on transporters in the CNS.
Neurochemistry international ( IF 4.4 ) Pub Date : 2018-12-17 , DOI: 10.1016/j.neuint.2018.12.006
Randy D Blakely 1 , Salah El Mestikawy 2 , Michael B Robinson 3
Affiliation  

The brain has specific properties that make it uniquely dependent upon transporters. This is the 3rd edition of a biennial special issue that originates from a scientific meeting devoted to studies of transporters and their relationship to brain function and to neurodevelopmental, neurologic, and psychiatric disorders. The field continues to rapidly evolve with advances in studies of structure that inform mechanism, with genetic analyses in humans revealing surprising aspects of biology, and with integrated cellular to whole animal analyses of the role of transporters in their control of physiology and pathophysiology. This special issue includes a sampling of review articles that address timely questions of the field followed by several primary research articles.

中文翻译:

不断变化的大脑:中枢神经系统转运蛋白的遗传学,生理学和治疗学观点。

大脑具有特定的特性,使其独特地依赖于转运蛋白。这是两年一次的第三期特刊,源于科学会议,该会议专门研究转运蛋白及其与脑功能,神经发育,神经系统和精神疾病的关系。随着告知机制的结构研究的发展,人类的遗传分析揭示了生物学的令人惊讶的方面以及整合了细胞到整个动物的转运蛋白在其控制生理和病理生理中的作用的综合分析,该领域继续迅速发展。本期特刊包括评论文章的样本,这些文章及时解决了该领域的问题,随后还发表了几篇主要研究文章。
更新日期:2018-12-17
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