Regression in children with epilepsy may involve loss of cognitive abilities, failure to progress or a slowing of developmental trajectory. A few seizures do not lead to regression. Large numbers of seizures may be associated with regression but the cause is an important cofounder. Individual spike discharges on EEG are associated with transient cognitive impairment and continuous spike discharges with regression. Regression may be global in continuous spike wave in slow sleep (CSWS) or specific (auditory agnosia) in Landau Kleffner syndrome. Regression is mild and transient in Rolandic Epilepsy or profound and permanent in West Syndrome. Epilepsy syndromes grouped under “epileptic encephalopathies” may lead to regression, although proof of this concept is not strong for many syndromes. The absence of cognitive assessment before epilepsy onset, the contribution of the cause and complications of treatment make for difficult methodological problems. The large majority of children with epilepsy do not have regression. There is need for more longitudinal studies of children with epileptic encephalopathies and other epilepsies associated with regression.

癫痫患儿的回归可能涉及认知能力的丧失，进展的失败或发育轨迹的减慢。少量癫痫发作不会导致消退。大量癫痫发作可能与消退有关，但原因是重要的共同创始人。脑电图上的个别峰值放电与短暂的认知障碍和持续的峰值放电与消退相关。缓慢睡眠（CSWS）的连续尖峰波或Landau Kleffner综合征的特定（听觉失常）可能是整体回归。在罗兰性癫痫中，回归是轻度和短暂的，而在西综合征中，回归是永久性的。癫痫综合症归类为“癫痫性脑病”可能导致消退，尽管这一概念的证据在许多综合症中并不充分。癫痫发作之前缺乏认知评估，原因和治疗并发症造成了困难的方法学问题。绝大多数患有癫痫病的儿童没有消退。有必要对患有癫痫性脑病和其他与回归相关的癫痫病的儿童进行更纵向的研究。