Five undescribed cycloartane-type triterpenoids, which were isolated for the first time from the genus, and a flavonoid glycoside together with 11 known compounds were isolated from the burs of Castanea crenata. The structures were elucidated based on the spectroscopic analysis of 1D and 2D NMR and MS data. All isolated compounds were evaluated for antiviral activities against HRV1B-, CVB3-, and PR8-infected cells. Most kaempferol derivatives showed statistically significant antiviral activities against HRV1B-infected cells. Among the tested compounds, kaempferol-3-O-[2″,6″-di-O-Z-p-coumaroyl]-β-d-glucopyranoside exhibited the most consistent and effective antiviral activities against all infections.

中文翻译：

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环阿烷型三萜衍生物和来自栗子的黄酮苷

首次从该属中分离得到 5 种未描述的环阿烷型三萜类化合物，以及一种黄酮苷和 11 种已知化合物，从板栗中分离得到。基于一维和二维核磁共振和质谱数据的光谱分析阐明了结构。评估了所有分离的化合物对 HRV1B、CVB3 和 PR8 感染细胞的抗病毒活性。大多数山奈酚衍生物对 HRV1B 感染的细胞显示出统计学上显着的抗病毒活性。在测试的化合物中，山奈酚-3-O-[2″,6″-di-OZp-coumaroyl]-β-d-吡喃葡萄糖苷对所有感染表现出最一致和最有效的抗病毒活性。