Mimicking the Secretory Action of a Gland by a Composite System Made of a pH-Responsive Surfactant-Based Hydrogel and a Dialysis Membrane,ACS Omega

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Mimicking the Secretory Action of a Gland by a Composite System Made of a pH-Responsive Surfactant-Based Hydrogel and a Dialysis Membrane
ACS Omega ( IF 3.7 ) Pub Date : 2018-12-06 00:00:00 , DOI: 10.1021/acsomega.8b02940
Alessio Cesaretti ₁ , Irene Di Guida ₁ , Naishka E. Caldero-Rodríguez _{1,

2} , Catia Clementi ₁ , Raimondo Germani ₁ , Pier Luigi Gentili ₁

Affiliation

The hydrogel obtained by a zwitterionic N-oxide surfactant is proposed as the core of a pH-responsive artificial gland model. The viscosity and pH variations, induced by pulse additions of acid and base, are investigated by a pyridinium salt and alizarin red S, respectively. The artificial gland model is implemented by enclosing the gel within a dialysis membrane, and its secretory action is tested by monitoring the release of a fluorescent acridinium salt.

中文翻译：

通过基于pH值的基于表面活性剂的水凝胶和渗析膜组成的复合系统模拟腺体的分泌作用

通过两性离子型N-氧化物表面活性剂获得的水凝胶被提议作为pH响应人工腺模型的核心。分别通过吡啶鎓盐和茜素红S考察了脉冲添加酸和碱引起的粘度和pH值变化。通过将凝胶包封在透析膜中来实现人工腺体模型，并通过监测荧光a啶鎓盐的释放来测试其分泌作用。

更新日期：2018-12-06

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