BACKGROUND Little is understood about the causes of adolescent onset idiopathic scoliosis (AIS). No prospective studies assessing the association between physical activity and idiopathic adolescent scoliosis have been carried out. We aimed to carry out the first prospective population-based study of this association. METHODS The Avon Longitudinal Study of Parents and Children (ALSPAC) collected self-reported measures of physical ability/activity at ages 18 months and 10 years. Objective measures of physical activity were collected by accelerometry at age 11 years. scoliosis was identified using the dxa scoliosis Method at age 15 years. Participants with scoliosis at age 10 years were excluded. RESULTS Of 4640 participants at age 15 years who had DXA scans, 267 (5.8%) had scoliosis. At age 18 months, those infants who were able to stand up without being supported were 66% less likely to have developed scoliosis by age 15 (P = 0.030) compared with infants who could not. Those children whose mothers reported they did most vigorous physical activity at age 10 years were 53% less likely to develop scoliosis (P = 0.027). Those children who did more objectively measured moderate/vigorous physical activity at age 11 were 30% less likely to have developed scoliosis (P < 0.001). Results were not affected by adjustment for age, gender, lean mass, fat mass or back pain. CONCLUSIONS We report reduced physical ability and activity as early as age 18 months in those who go on to develop scoliosis by age 15 years. Further research is justified to examine the mechanisms underlying this association.

中文翻译：

---

体育活动与脊柱侧弯之间的关联：一项前瞻性队列研究。

背景 关于青少年发作的特发性脊柱侧凸 (AIS) 的病因知之甚少。尚未进行评估体育活动与特发性青少年脊柱侧凸之间关联的前瞻性研究。我们的目标是对该关联进行第一项前瞻性的基于人群的研究。方法 雅芳父母和儿童纵向研究 (ALSPAC) 收集了 18 个月和 10 岁时自我报告的身体能力/活动量度。在 11 岁时通过加速度计收集客观的身体活动测量值。脊柱侧弯是在 15 岁时使用 dxa 脊柱侧凸方法确定的。10 岁时患有脊柱侧凸的参与者被排除在外。结果 在 15 岁接受 DXA 扫描的 4640 名参与者中，267 名 (5.8%) 患有脊柱侧弯。在 18 个月大时，与不能站立的婴儿相比，那些能够在没有支撑的情况下站立的婴儿在 15 岁时发生脊柱侧弯的可能性降低了 66%（P = 0.030）。那些母亲报告说他们在 10 岁时进行了最剧烈的体育活动的孩子患脊柱侧凸的可能性降低了 53% (P = 0.027)。那些在 11 岁时进行更客观测量的中等/剧烈体力活动的儿童患脊柱侧凸的可能性降低了 30%（P < 0.001）。结果不受年龄、性别、瘦体重、脂肪量或背痛调整的影响。结论 我们报告了那些在 15 岁时继续发展为脊柱侧弯的人，早在 18 个月大时身体能力和活动量就会下降。进一步的研究有理由检查这种关联背后的机制。