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Pharmacology of medications used for ovarian stimulation
Best Practice & Research Clinical Endocrinology & Metabolism ( IF 6.1 ) Pub Date : 2018-11-12 , DOI: 10.1016/j.beem.2018.10.002
Alexander M. Quaas , Richard S. Legro

Medications to stimulate the ovaries may be used to induce ovulation in patients with anovulatory infertility or to hyperstimulate the ovaries in a controlled fashion in ovulatory patients as part of assisted reproductive treatments (ART).

The pharmacology of all current major medications used to stimulate ovarian function is reviewed in this article, including letrozole, clomiphene citrate, gonadotropins, and pulsatile gonadotropin releasing hormone (GnRH). Novel potential compounds and adjuvant treatment approaches are also discussed, such as kisspeptin agonists and androgens.



中文翻译:

卵巢刺激药物的药理学

作为辅助生殖治疗(ART)的一部分,刺激卵巢的药物可用于在无排卵性不育症患者中诱导排卵,或在排卵患者中以受控方式过度刺激卵巢。

本文综述了所有目前用于刺激卵巢功能的主要药物的药理学,包括来曲唑,柠檬酸克罗米芬,促性腺激素和搏动性促性腺激素释放激素(GnRH)。还讨论了新的潜在化合物和辅助治疗方法,例如亲肽素激动剂和雄激素。

更新日期:2018-11-12
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