Chemical and Biomolecule Sensing with Organic Field-Effect Transistors,Chemical Reviews

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Chemical and Biomolecule Sensing with Organic Field-Effect Transistors
Chemical Reviews ( IF 51.4 ) Pub Date : 2018-11-07 00:00:00 , DOI: 10.1021/acs.chemrev.8b00016
Hui Li ₁ , Wei Shi _{1,

2} , Jian Song ₁ , Hyun-June Jang ₁ , Jennifer Dailey ₁ , Junsheng Yu ₂ , Howard E. Katz ₁

Affiliation

The strong and controllable chemical sensitivity of organic semiconductors (OSCs) and the amplification capability of transistors in circuits make use of OSC-based field-effect transistors compelling for chemical sensors. Analytes detected and assayed range from few-atom gas-phase molecules that may have adverse health and security implications to biomacromolecules (proteins, nucleic acids) that may be markers for physiological processes and medical conditions. This review highlights recent progress in organic field-effect transistor (OFET) chemical sensors, emphasizing advances from the past 5 years and including aspects of OSC morphology and the role of adjacent dielectrics. Design elements of the OSCs and various formats for the devices are illustrated and evaluated. Challenges associated with the present state of the art and future opportunities are also discussed.

中文翻译：

有机场效应晶体管的化学和生物分子传感

有机半导体（OSC）的强大且可控的化学敏感性以及电路中晶体管的放大能力充分利用了基于OSC的场效应晶体管，该晶体管极受化学传感器的青睐。检测和分析的分析物包括可能对健康和安全性有不利影响的少数原子气相分子，以及可能是生理过程和医学状况的标志物的生物大分子（蛋白质，核酸）。这篇综述重点介绍了有机场效应晶体管（OFET）化学传感器的最新进展，强调了过去5年的进展，包括OSC形态和相邻电介质作用的方面。图示并评估了OSC的设计元素和设备的各种格式。

更新日期：2018-11-07

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