The microbial life that exists in harsh habitats of low pH possess several unique characteristics, which assign interesting qualities to these microorganisms and enable them to thrive in such a harsh environment. Among microorganisms inhabiting low pH environments, fungi are the second largest reported organisms. These acidophilic fungi are the main source of acid–stable enzymes that could be utilized in many industries including paper, leather making, food and feed industries, where the efficacy of commonly available enzymes is limited by challenges like stability and functional kinetics. The current review discusses the acidophilic fungi with emphasis on their diversity and pH homeostasis mechanisms adopted against low pH environments. In addition, an overview about the acid–stable enzymes obtained from these acidophilic fungi, their main sources and potential applications have also been discussed.

在低pH值的恶劣栖息地中存在的微生物生命具有几个独特的特征，这些特征赋予这些微生物以有趣的品质，并使它们能够在如此恶劣的环境中壮成长。在低pH值环境中居住的微生物中，真菌是第二大报告生物。这些嗜酸真菌是酸稳定酶的主要来源，可用于许多工业，包括造纸，皮革制造，食品和饲料工业，这些工业中常用酶的功效受到诸如稳定性和功能动力学等挑战的限制。当前的评论讨论了嗜酸性真菌，重点是针对低pH环境采用的多样性和pH稳态机制。此外，概述了从这些嗜酸真菌中获得的酸稳定酶，