The objective of this study was to determine the effect of laparoscopic sleeve gastrectomy (LSG) on blood pressure in private practice settings. This study involved a retrospective review of 870 consecutive adult patients >18 y of age who underwent LSG over a period of 12 mo in a private bariatric surgery center. Data were collected from the preoperative and postoperative follow-up visits at 1, 3, 6, and 12 mo. The study population consists of 694 hypertensive and 176 normotensive patients. From the baseline to 12 mo after LSG, (1) mean body weight/body mass index decreased from 123 kg/44 kg/m² to 94 kg/34 kg/m² (P < .001); (2) mean systolic/diastolic blood pressure in hypertensive patients decreased from 131.9/79.9 to 127.6/77.1 mm Hg (P < .001); 3) only mean systolic blood pressure decreased in normotensive patients from 117.5 to 114.0 mm Hg (P < .001). One month after LSG, mean systolic blood pressure had decreased from 131.9 to 126.2 mm Hg (P < 0. 001) and the average number of antihypertensive medications per patient declined from 1.5 at the baseline to 0.6 (P < .001). Over the following 11 mo, blood pressure remained stable despite reduced antihypertensive therapy. Patients requiring more than two antihypertensive agents fell from 49% at the baseline to 22% at 12 mo. Hypertension resolved in 34% of patients. Linear regression analysis showed no association between change in body weight and change in systolic blood pressure. Within 1 mo of LSG, hypertensive patients experienced a significant decline in systolic blood pressure and antihypertensive therapy that remains unchanged at 12 mo in the face of major reductions in antihypertensive medications. Weight loss and blood pressure reduction may not be directly related.

这项研究的目的是确定在私人执业环境中腹腔镜袖胃切除术（LSG）对血压的影响。这项研究包括对一家私人减肥手术中心连续12个月接受LSG的870例连续18岁以上的成年患者的回顾性回顾。分别从术前，术后1、3、6和12个月的随访中收集数据。研究人群包括694位高血压患者和176位血压正常的患者。从基线到LSG后12个月，（1）平均体重/体重指数从123 kg / 44 kg / m ²降至94 kg / 34 kg / m ²（P  <.001）；（2）高血压患者的平均收缩压/舒张压从131.9 / 79.9降至127.6 / 77.1 mm Hg（P <.001）; 3）仅正常血压患者的平均收缩压从117.5毫米汞柱降低到114.0毫米汞柱（P  <.001）。LSG治疗后一个月，平均收缩压从131.9 mm Hg降低至126.2 mm Hg（P  <0. 001），每位患者的平均降压药物数量从基线的1.5降至0.6（P <.001）。在接下来的11个月中，尽管降压治疗减少，血压仍保持稳定。需要两种以上降压药的患者从基线时的49％降至12个月时的22％。高血压在34％的患者中得到解决。线性回归分析显示体重变化与收缩压变化之间没有关联。在LSG的1个月内，面对降压药物的大量减少，高血压患者的收缩压和抗高血压治疗均显着下降，在12个月时保持不变。体重减轻和血压降低可能不直接相关。