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Facet Joints of the Spine: Structure–Function Relationships, Problems and Treatments, and the Potential for Regeneration
Annual Review of Biomedical Engineering ( IF 12.8 ) Pub Date : 2018-06-04 00:00:00 , DOI: 10.1146/annurev-bioeng-062117-120924
Siobhan A. O'Leary 1 , Nikolaos K. Paschos 2 , Jarrett M. Link 3 , Eric O. Klineberg 4 , Jerry C. Hu 3 , Kyriacos A. Athanasiou 3
Affiliation  

The zygapophysial joint, a diarthrodial joint commonly referred to as the facet joint, plays a pivotal role in back pain, a condition that has been a leading cause of global disability since 1990. Along with the intervertebral disc, the facet joint supports spinal motion and aids in spinal stability. Highly susceptible to early development of osteoarthritis, the facet is responsible for a significant amount of pain in the low-back, mid-back, and neck regions. Current noninvasive treatments cannot offer long-term pain relief, while invasive treatments can relieve pain but fail to preserve joint functionality. This review presents an overview of the facet in terms of its anatomy, functional properties, problems, and current management strategies. Furthermore, this review introduces the potential for regeneration of the facet and particular engineering strategies that could be employed as a long-term treatment.

中文翻译:


脊柱小关节:结构-功能关系,问题和治疗,以及再生的潜力

po关节,通常称为小关节,在腰痛中起关键作用,自1990年以来,这种疼痛一直是导致全球残疾的主要原因。小关节与椎间盘一起支持脊柱运动和有助于脊柱稳定。该小面高度易受骨关节炎的早期发展的影响,在腰部,中背部和颈部区域引起大量疼痛。当前的非侵入性治疗不能长期缓解疼痛,而侵入性治疗可以缓解疼痛但不能保持关节功能。这篇综述从其解剖结构,功能特性,问题和当前的管理策略方面对该方面进行了概述。此外,

更新日期:2018-06-04
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