Ovarian cancer (OC), one of the gynecologic malignancies with high invasive and metastatic potential, has a low survival rate in females. Although cytoreductive surgery combined with chemotherapy is the principal treatment for OC, the prognosis remains poor, and the recurrence rate of OC remains high. It is urgent to explore novel biomarkers for the diagnosis and prognosis of OC, as well as therapeutic targets. Circular RNAs (circRNAs) are a class of highly conserved, stable and abundant noncoding RNAs (ncRNAs). Recent studies have shown that circRNAs participate in OC progression by regulating various processes, including cell proliferation, migration, invasion and apoptosis. In addition, circRNAs are potential biomarkers for OC diagnosis and prognosis. This review provides an overview of recent findings on circRNAs in OC, including their functions and molecular mechanisms, and discusses their potential roles as diagnostic and prognostic biomarkers, as well as therapeutic targets for OC.

中文翻译：

---

环状RNA及其在卵巢癌中作为诊断和预后生物标志物的新兴作用。

卵巢癌（OC）是具有高浸润和转移潜能的妇科恶性肿瘤之一，在女性中存活率较低。尽管减细胞术联合化学疗法是OC的主要治疗方法，但预后仍然很差，OC的复发率仍然很高。迫切需要探索新颖的生物标志物以诊断和诊断OC以及治疗靶标。环状RNA（circRNA）是一类高度保守，稳定和丰富的非编码RNA（ncRNA）。最近的研究表明，circRNA通过调节各种过程（包括细胞增殖，迁移，侵袭和凋亡）参与OC进展。此外，circRNA是OC诊断和预后的潜在生物标志物。这篇综述概述了OC中circRNA的最新发现，