Since its introduction to the diagnostic pathway for prostate cancer management, prostate-specific membrane antigen (PSMA)-ligand PET has demonstrated great potential. PSMA-ligand imaging is increasingly influencing therapeutic decision making, although its impact on patient outcomes still needs to be defined. One relatively new application, enabled through chemical and engineering efforts, is PSMA-guided surgery. This review highlights the potential of PSMA-guided surgery and discusses its implications in lymph node dissection in primary and recurrent prostate cancer.

中文翻译：

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前列腺特异性膜抗原引导手术。

自从将前列腺特异性膜抗原（PSMA）配体PET引入前列腺癌管理的诊断途径以来，已显示出巨大的潜力。尽管仍然需要确定PSMA配体成像对患者预后的影响，但其越来越多地影响治疗决策。通过化学和工程方面的努力，一种相对较新的应用是PSMA引导的手术。这篇综述强调了PSMA引导手术的潜力，并讨论了其在原发性和复发性前列腺癌淋巴结清扫术中的意义。